Hiki ke unuhi maoli ʻia ʻo Arbutin mai nā mea kanu e like me ka bearberry a hoʻohui ʻia e ke ʻano kemika. ʻO Arbutin Synthesized i kēia manawa kekahi o nā mea hoʻohana hypopigmenting i hoʻohana nui ʻia i nā mea hoʻonaninani. Hiki i ka Arbutin ke hoʻomaʻemaʻe i ka ʻili i ʻike nui ʻia, no laila ua hoʻohana ʻia ka arbutin i ka uila a me nā mea keʻokeʻo i loko o nā mea hoʻonaninani.
Aia ʻo Arbutin iā Alpha-Arbutin a me Beta-Arbutin. No ka ʻike kikoʻī o ka huahana, hiki iā ʻoe ke kipa i ka loulou: /alpha-arbutin-huahana/
Nā ʻāpana ʻenehana nui:
| Nā mea | Alpha-Arbutin | Beta-Arbutin |
| Ka nana aku | Pauda Crystal Keʻokeʻo | ʻO ka pauka keʻokeʻo kristal |
| Hoʻāʻo | 99.0% min. | 99.5% min |
| Lae hehee | 202~207 ℃ | 198.5~201.5 ℃ |
| Ka malamalama o ka wai | ʻO ka māliko, kala ʻole, ʻaʻohe mea i hoʻopaneʻe ʻia | ʻO ka māliko, kala ʻole, ʻaʻohe mea i hoʻopaneʻe ʻia |
| Akaka a me ke kala o ka hoʻonā | Akaka a kala ole | |
| pH waiwai o 1% wai | 5.0～7.0 | 5.0～7.0 |
| ʻO ka hoʻololi ʻana i ka optical kikoʻī | 【ɑ】D20=+176~184° | 【a】D20=-66±2º |
| Arsenic | ≤2 ppm | ≤2 ppm |
| Hydroquinone | ≤10 ppm | ≤10 ppm |
| Metala kaumaha | ≤10 ppm | ≤10 ppm |
| Pohō ma ka maloʻo | ≤0.5% | ≤0.5% |
| Ke koena puhi | ≤0.5% | ≤0.5% |
| Patogen | Bakā: ≤100cfg/g max.Fungus: ≤100 cfu/g | Bakteria:≤300cfu/gFungus：≤100cfu/g |
Nā kumu o ka pigmentation:
Hoʻoholo ʻia ka waihoʻoluʻu ʻili e ka hui ʻana o nā kala like ʻole. Loaʻa ka waihoʻoluʻu ʻeleʻele mai nā puaʻa eumelanin a me phaeomelanin, i hana ʻia i loko o nā pūnaewele epidermal kūikawā i kapa ʻia nā melanocytes. Hoʻokumu ʻia ka enzyme tyrosinase i loko o kēia mau melanocytes. ʻO kāna hoʻāla ʻia e ka kukui UV e hoʻāla i ka melanogenesis, kahi ʻano paʻakikī o nā hopena kemika enzymatic e alakaʻi i ka hoʻokumu ʻana o nā melanins, e alakaʻi ana i nā discolorations i makemake ʻole ʻia ma ka ʻili o ka ʻili e hōʻike pinepine ʻia e like me nā makahiki, melasma a i ʻole freckles.
Mechanism o ka hana:
ʻO Arbutin kahi hydroquinone glycosylated e hele mai ana ma nā ʻano ʻelua, ʻo ka Alpha-Arbutin a me ka Beta-Arbutin. Manaʻo ʻia ʻo Arbutins ka mea hoʻomaʻamaʻa uila maikaʻi loa no ka mea e kōkua ana i ka pale ʻana i ka epidermal melanin biosynthesis. Kōkua ia i ka pale ʻana i ka biosynthesis melanin epidermal ma ke kāohi ʻana i ka oxidation enzymatic o Tyrosine a me Dopa.
Ua hōʻike ʻia ʻo Alpha-Arbutin i nā hopena ʻoi aku ka maikaʻi, ʻoiai ke hoʻohālikelike ʻia i kāna mau molekele like-chemically, hydroquinone a me beta-arbutin. Ma waho aʻe o ka ʻoi aku ka maikaʻi, ʻoi aku ka maikaʻi o ka palekana palekana i hoʻohālikelike ʻia me ka hydroquinone, a ʻoi aku ka paʻa i ka wā e hoʻohālikelike ʻia me beta-arbutin. ʻO kēia mau hiʻohiʻona ka mea e hele ai no ka hoʻomaʻamaʻa ʻana i ka ʻili a me ka hōʻemi ʻana i nā wahi ʻeleʻele ma ka ʻili.
Hydroquinone vs Alpha Arbutin
Ua manaʻo ʻia ʻo Hydroquinone i ke kūlana gula no ka mālama ʻana i ka hyperpigmentation. ʻOiai e hōʻike ana nā haʻawina hauʻoli i nā pane depigmentation maikaʻi loa i hoʻokomo ʻia e 2% hydroquinone, ua hōʻike ʻia hoʻi ia e hoʻokau i nā hopena ʻino. ʻO kēia mau mea he ochronosis exogenous, cataract, pigmented colloid milia, sclera, a me nail pigmentation, nalowale o ka elasticity o ka ʻili, hōʻemi i ka hoʻōla ʻana i ka ʻeha a me ka hoʻopuka ʻana i kahi ʻala iʻa ʻino. Hiki i ka hydroquinone ke hoʻopōʻino i ka DNA. Hoʻopau kēia mau hopena i ka hoʻohana ʻana i ka hydroquinone.
Ua hōʻike ʻia ʻo Alpha-Arbutin e hoʻokō i kahi hopena uila maikaʻi loa me ka ʻole o nā mea ʻawaʻawa a me nā huhū e pili ana me ka hydroquinone.
Nā huahana mālama ʻili me ka arbutin:Palika ʻIli, Palika Freckle, Palika Momi Kiʻekiʻe a me ka Maka Maka.
Ka manawa hoʻouna: Mar-23-2021